The medical literature is exploding with the dangers of insulin resistance in the increase of cardiovascular disease and other disease entities.

It is reported that chronic insulin resistance is also associated with various types of cancer such as colorectal cancer, pancreatic cancer, endometrial cancer, and breast cancer.

Insulin resistance is when cells in your muscles, fat, and liver don't respond well to insulin and can't use glucose from your blood for energy. To make up for it, your pancreas makes more insulin. Over time, your blood sugar levels go up.

Effective Treatment for Insulin Resistance

• Carbohydrates such as simple sugars, grains and starchy vegetables should be avoided as they stimulate insulin secretion. 
• Carbohydrates should be replaced with higher protein containing foods and non-starchy vegetables.
• Adequate vitamin D intake
• Aerobic and resistance training, High-Intensity Interval Training (HIIT), has been found to be superior to low intensity cardio. Of course I suggest that people completely out of shape to work their way up to HIIT.  Start out slow
• Some exercise is better than none
• Get 6-8 hours of uninterrupted nightly sleep
• Reduce stress: meditation is recommended
• Get adequate magnesium intake and make sure it is the correct type of magnesium
• Berberine supplementation

Conclusion

I recommend that everyone takes insulin resistance very seriously. The implications of being associated with increased cardiovascular disease and cancer are overwhelming. The following robust list of peer reviewed citations should be reviewed.